Lloyd, Matthew G., D'Acunto, Mariantonietta, Taylor, Richard J K orcid.org/0000-0002-5880-2490 et al. (1 more author) (2016) A selective C-H insertion/olefination protocol for the synthesis of α-methylene-γ-butyrolactone natural products. Organic and Biomolecular Chemistry. pp. 1641-1645. ISSN 1477-0539
Abstract
A regio- and stereoselective one-pot C-H insertion/olefination protocol has been developed for the late stage installation of α-methylene-γ-butyrolactones into conformationally restricted cyclohexanol-derivatives. The method has been successfully applied in the total synthesis of eudesmanolide natural product frameworks, including α-cyclocostunolide.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Royal Society of Chemistry 2016. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) The University of York |
Depositing User: | Pure (York) |
Date Deposited: | 25 Feb 2016 12:00 |
Last Modified: | 19 Mar 2025 00:06 |
Published Version: | https://doi.org/10.1039/c5ob02579f |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1039/c5ob02579f |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:95485 |
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