Lloyd, Matthew G., D'Acunto, Mariantonietta, Taylor, Richard J K orcid.org/0000-0002-5880-2490 et al. (1 more author) (2016) A selective C-H insertion/olefination protocol for the synthesis of α-methylene-γ-butyrolactone natural products. Organic and Biomolecular Chemistry. pp. 1641-1645. ISSN: 1477-0539
Abstract
A regio- and stereoselective one-pot C-H insertion/olefination protocol has been developed for the late stage installation of α-methylene-γ-butyrolactones into conformationally restricted cyclohexanol-derivatives. The method has been successfully applied in the total synthesis of eudesmanolide natural product frameworks, including α-cyclocostunolide.
Metadata
| Item Type: | Article | 
|---|---|
| Authors/Creators: | 
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| Copyright, Publisher and Additional Information: | © Royal Society of Chemistry 2016. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details | 
| Dates: | 
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| Institution: | The University of York | 
| Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) The University of York | 
| Depositing User: | Pure (York) | 
| Date Deposited: | 25 Feb 2016 12:00 | 
| Last Modified: | 16 Sep 2025 23:50 | 
| Published Version: | https://doi.org/10.1039/c5ob02579f | 
| Status: | Published | 
| Refereed: | Yes | 
| Identification Number: | 10.1039/c5ob02579f | 
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:95485 | 
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