The Concise Guide to PHARMACOLOGY 2013/14: overview.

Abstract

The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties from the IUPHAR database. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. This compilation of the major pharmacological targets is divided into seven areas of focus: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors & Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

Metadata

Item Type:	Article
Authors/Creators:	Alexander, SP Benson, HE Faccenda, E Pawson, AJ Sharman, JL McGrath, JC Catterall, WA Spedding, M Peters, JA Harmar, AJ CGTP Collaborators Abul-Hasn, N Anderson, CM Anderson, CM Araiksinen, MS Arita, M Arthofer, E Barker, EL Barratt, C Barnes, NM Bathgate, R Beart, PM Belelli, D Bennett, AJ Birdsall, NJ Boison, D Bonner, TI Brailsford, L Bröer, S Brown, P Calo, G Carter, WG Catterall, WA Chan, SL Chao, MV Chiang, N Christopoulos, A Chun, JJ Cidlowski, J Clapham, DE Cockcroft, S Connor, MA Cox, HM Cuthbert, A Dautzenberg, FM Davenport, AP Dawson, PA Dent, G Dijksterhuis, JP Dollery, CT Dolphin, AC Donowitz, M Dubocovich, ML Eiden, L Eidne, K Evans, BA Fabbro, D Fahlke, C Farndale, R Fitzgerald, GA Fong, TM Fowler, CJ Fry, JR Funk, CD Futerman, AH Ganapathy, V Gaisnier, B Gershengorn, MA Goldin, A Goldman, ID Gundlach, AL Hagenbuch, B Hales, TG Hammond, JR Hamon, M Hancox, JC Hauger, RL Hay, DL Hobbs, AJ Hollenberg, MD Holliday, ND Hoyer, D Hynes, NA Inui, KI Ishii, S Jacobson, KA Jarvis, GE Jarvis, MF Jensen, R Jones, CE Jones, RL Kaibuchi, K Kanai, Y Kennedy, C Kerr, ID Khan, AA Klienz, MJ Kukkonen, JP Lapoint, JY Leurs, R Lingueglia, E Lippiat, J Lolait, SJ Lummis, SC Lynch, JW MacEwan, D Maguire, JJ Marshall, IL May, JM McArdle, CA McGrath, JC Michel, MC Millar, NS Miller, LJ Mitolo, V Monk, PN Moore, PK Moorhouse, AJ Mouillac, B Murphy, PM Neubig, RR Neumaier, J Niesler, B Obaidat, A Offermanns, S Ohlstein, E Panaro, MA Parsons, S Pwrtwee, RG Petersen, J Pin, JP Poyner, DR Prigent, S Prossnitz, ER Pyne, NJ Pyne, S Quigley, JG Ramachandran, R Richelson, EL Roberts, RE Roskoski, R Ross, RA Roth, M Rudnick, G Ryan, RM Said, SI Schild, L Sanger, GJ Scholich, K Schousboe, A Schulte, G Schulz, S Serhan, CN Sexton, PM Sibley, DR Siegel, JM Singh, G Sitsapesan, R Smart, TG Smith, DM Soga, T Stahl, A Stewart, G Stoddart, LA Summers, RJ Thorens, B Thwaites, DT Toll, L Traynor, JR Usdin, TB Vandenberg, RJ Villalon, C Vore, M Waldman, SA Ward, DT Willars, GB Wonnacott, SJ Wright, E Ye, RD Yonezawa, A Zimmermann, M
Copyright, Publisher and Additional Information:	© 2013 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords:	Databases, Pharmaceutical; Humans; Ligands; Molecular Targeted Therapy; Pharmaceutical Preparations; Pharmacology
Dates:	Published: 17 December 2013
Institution:	The University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection and Immunity (Sheffield)
Depositing User:	Symplectic Sheffield
Date Deposited:	26 Feb 2016 16:40
Last Modified:	03 Nov 2017 03:34
Published Version:	http://dx.doi.org/10.1111/bph.12444
Status:	Published
Publisher:	Nature Publishing Group
Identification Number:	10.1111/bph.12444
Related URLs:	Author
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:95031

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The Concise Guide to PHARMACOLOGY 2013/14: overview.

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