Cullen, W., Thomas, K.A., Hunter, C.A. et al. (1 more author) (2015) pH-Controlled selection between one of three guests from a mixture using a coordination cage host. Chemical Science, 6 (7). pp. 4025-4028. ISSN 2041-6520
Abstract
We demonstrate the use of a simple pH swing to control the selection of one of three different guests from aqueous solution by a coordination cage host. Switching between different guests is based on the fact that neutral organic guests bind strongly in the cage due to the hydrophobic effect, but for acidic or basic guests, the charged (protonated or deprotonated) forms are hydrophilic and do not bind. The guests used are adamantane-1,3-dicarboxylic acid (H2A) which binds at low pH when it is neutral but not when it is deprotonated; 1-amino-adamantane (B) which binds at high pH when it is neutral but not when it is protonated; and cyclononanone (C) whose binding is not pH dependent and is therefore the default guest at neutral pH. Thus an increase in pH can reversibly switch the host between the three different bound states cageH2A (at low pH), cageC (at medium pH), and cageB (at high pH) in succession.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015 Cullen et al. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 28 Jan 2016 12:36 |
Last Modified: | 28 Jan 2016 12:36 |
Status: | Published |
Publisher: | RSC |
Refereed: | Yes |
Identification Number: | 10.1039/c5sc01475a |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:92846 |