Peckham, D, Williams, K, Wynne, S et al. (3 more authors) (2016) Fungal contamination of nebuliser devices used by people with cystic fibrosis. Journal of Cystic Fibrosis, 15 (1). pp. 74-77. ISSN 1569-1993
Abstract
Background: Poor nebuliser hygiene can result in bacterial contamination and risk of infections. The aim of this study was to assess the prevalence of fungal contamination of nebulisers used by adults with cystic fibrosis. Methods: 170 nebulisers from 149 subjects were screened by wetting a sterile cotton swab with sterile water and swabbing each drug chamber. The swab was then plated out on Sabouraud and on Scel+ agar and incubated at 27⁰C for up to two weeks. Results: Fungal cultures were positive in 86 (57.7%) patient's devices. In 28/149 (18.8%), 39/149 (26.2%), 47/149 (31.5%) and 20/149 (13.4%) of subjects Aspergillus species, yeasts, moulds and both yeasts and moulds were isolated respectively. There was no difference in contamination rates between different devices. Conclusion: Nebuliser devices are frequently contaminated by moulds and yeasts and emphasis should be placed on ensuring adequate nebuliser hygiene.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved. This is an author produced version of a paper published in Journal of Cystic Fibrosis. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Biofilm; fungi; nebuliser; device |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Translational Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 23 Dec 2015 11:34 |
Last Modified: | 23 Jun 2016 00:48 |
Published Version: | http://dx.doi.org/10.1016/j.jcf.2015.06.004 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.jcf.2015.06.004 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:92711 |