Reynolds, JE, Licari, MK, Billington, J orcid.org/0000-0003-0995-8875 et al. (5 more authors) (2015) Mirror neuron activation in children with developmental coordination disorder: A functional MRI study. International Journal of Developmental Neuroscience, 47 (B). pp. 309-319. ISSN 0736-5748
Abstract
The aim of this study was to reveal cortical areas that may contribute to the movement difficulties seen in children with Developmental Coordination Disorder (DCD). Specifically, we hypothesized that there may be a deficit in the mirror neuron system (MNS), a neural system that responds to both performed and observed actions. Using functional MRI, 14 boys with DCD (x¯=10.02 years±1.28, range=8.33-11.17 years) and 12 typically developing controls (x¯=10.10 years±1.16, range=8.02-12 years) were scanned observing, executing and imitating a finger sequencing task using their right hand. Cortical activations of mirror neuron regions, including posterior inferior frontal gyrus, ventral premotor cortex, anterior inferior parietal lobule and superior temporal sulcus were examined. Children with DCD had decreased cortical activation mirror neuron related regions, including the precentral gyrus and inferior frontal gyrus, as well as in the posterior cingulate and precuneus complex when observing the sequencing task. Region of interest analysis revealed lower activation in the pars opercularis, a primary MNS region, during imitation in the DCD group compared to controls. These findings provide some preliminary evidence to support a possible MNS dysfunction in children with DCD.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015, Elsevier Ltd. This is an author produced version of a paper published in International Journal of Developmental Neuroscience. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Developmental coordination disorder (DCD); Imitation; Mirror neuron system (MNS); Functional magnetic resonance imaging (fMRI); Cortical function |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Psychology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 27 Nov 2015 14:31 |
Last Modified: | 19 Mar 2019 16:37 |
Published Version: | http://dx.doi.org/10.1016/j.ijdevneu.2015.10.003 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.ijdevneu.2015.10.003 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:92289 |