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Dall'Ara, E., Barber, D. and Viceconti, M. (2014) About the inevitable compromise between spatial resolution and accuracy of strain measurement for bone tissue: A 3D zero-strain study. Journal of Biomechanics, 47 (12). 2956 - 2963. ISSN 0021-9290
Abstract
The accurate measurement of local strain is necessary to study bone mechanics and to validate micro computed tomography (μCT) based finite element (FE) models at the tissue scale. Digital volume correlation (DVC) has been used to provide a volumetric estimation of local strain in trabecular bone sample with a reasonable accuracy. However, nothing has been reported so far for μCT based analysis of cortical bone. The goal of this study was to evaluate accuracy and precision of a deformable registration method for prediction of local zero-strains in bovine cortical and trabecular bone samples. The accuracy and precision were analyzed by comparing scans virtually displaced, repeated scans without any repositioning of the sample in the scanner and repeated scans with repositioning of the samples.The analysis showed that both precision and accuracy errors decrease with increasing the size of the region analyzed, by following power laws. The main source of error was found to be the intrinsic noise of the images compared to the others investigated. The results, once extrapolated for larger regions of interest that are typically used in the literature, were in most cases better than the ones previously reported. For a nodal spacing equal to 50 voxels (498. μm), the accuracy and precision ranges were 425-692. με and 202-394. με, respectively. In conclusion, it was shown that the proposed method can be used to study the local deformation of cortical and trabecular bone loaded beyond yield, if a sufficiently high nodal spacing is used.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2014 Elsevier Ltd. This is an author produced version of a paper subsequently published in Journal of Biomechanics. Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
Keywords: | Bone; DVC; MicroCT; Registration; Strain |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Mechanical Engineering (Sheffield) The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection, Immunity and Cardiovascular Disease |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 07 Oct 2015 15:36 |
Last Modified: | 03 Nov 2017 16:43 |
Published Version: | http://dx.doi.org/10.1016/j.jbiomech.2014.07.019 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.jbiomech.2014.07.019 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:90509 |
Available Versions of this Item
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About the inevitable compromise between spatial resolution and accuracy of strain measurement for bone tissue: A 3D zero-strain study. (deposited 19 Mar 2015 12:01)
- About the inevitable compromise between spatial resolution and accuracy of strain measurement for bone tissue: A 3D zero-strain study. (deposited 07 Oct 2015 15:36) [Currently Displayed]