The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease

Bhattacharjee, A, Reuter, S, Trojnár, E et al. (9 more authors) (2015) The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease. Journal of Biological Chemistry, 290 (15). 9500 - 9510. ISSN 0021-9258

Metadata

Item Type: Article
Authors/Creators:
  • Bhattacharjee, A
  • Reuter, S
  • Trojnár, E
  • Kolodziejczyk, R
  • Seeberger, H
  • Hyvärinen, S
  • Uzonyi, B
  • Szilágyi, Á
  • Prohászka, Z
  • Goldman, A
  • Józsi, M
  • Jokiranta, TS
Copyright, Publisher and Additional Information:

© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Author's Choice—Final version full access. This article is licensed under the Creative Commons Attribution 3.0 Unported license.
Keywords: Autoimmune Disease; Autoimmunity; Immunoglobulin G (lgG); Immunology; X-ray Crystallography; Thrombotic Microangiopathy; Atypical Hemolytic Uremic Syndrome; Complement Regulation; Structure-Function Study
Dates:
  • Published: 10 April 2015
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 09 Oct 2015 10:09
Last Modified: 09 Oct 2015 10:09
Published Version: http://dx.doi.org/10.1074/jbc.M114.630871
Status: Published
Publisher: American Society for Biochemistry and Molecular Biology
Identification Number: 10.1074/jbc.M114.630871
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