Humphries, MP, Jordan, VC and Speirs, V (2015) Obesity and male breast cancer: Provocative parallels? BMC Medicine, 13 (1). 134. ISSN 1741-7015
Abstract
While rare compared to female breast cancer the incidence of male breast cancer (MBC) has increased in the last few decades. Without comprehensive epidemiological studies, the explanation for the increased incidence of MBC can only be speculated. Nevertheless, one of the most worrying global public health issues is the exponential rise in the number of overweight and obese people, especially in the developed world. Although obesity is not considered an established risk factor for MBC, studies have shown increased incidence among obese individuals. With this observation in mind, this article highlights the correlation between the increased incidence of MBC and the current trends in obesity as a growing problem in the 21<sup>st</sup> century, including how this may impact treatment. With MBC becoming more prominent we put forward the notion that, not only is obesity a risk factor for MBC, but that increasing obesity trends are a contributing factor to its increased incidence.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015 Humphries et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
Keywords: | Aromatase; Aromatase inhibitor; Body mass index; Estrogen; Incidence; Obesity; Risk factor; Selective estrogen receptor modulator; Tamoxifen |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 06 Oct 2015 11:37 |
Last Modified: | 26 Feb 2019 09:23 |
Published Version: | http://dx.doi.org/10.1186/s12916-015-0380-x |
Status: | Published |
Publisher: | BioMed Central |
Identification Number: | 10.1186/s12916-015-0380-x |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:88945 |
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