Tuplin, AK orcid.org/0000-0003-2524-707X (2015) Diverse roles and interactions of RNA structures during the replication of positive-stranded RNA viruses of humans and animals. Journal of General Virology, 96. pp. 1497-1503. ISSN 1465-2099
Abstract
Positive-stranded RNA viruses include important human, animal and plant pathogens. Their genomes are able to fold into complex structures stabilized by base pairing between individual nucleotides, many of which are highly conserved and have essential functions during virus replication. With new studies and technological advances the diversity of roles, mechanisms and interactions in which such structured viral RNA functions is becoming increasingly clear. It is also evident that many RNA structures do not function as discrete elements but through mechanisms involving multiple, long-range and often dynamic RNARNA interactions. Through a range of examples and recent advances, this review illustrates the diverse roles and mechanisms of structured viral RNA during the replication of positive-stranded RNA viruses infecting humans and animals.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015, The Author. Published by the Microbiology Society. This is an author produced version of a paper published in Journal of General Virology. Uploaded in accordance with the publisher's self-archiving policy. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 08 Jul 2015 09:17 |
Last Modified: | 15 Nov 2016 23:45 |
Published Version: | http://dx.doi.org/10.1099/vir.0.000066 |
Status: | Published |
Publisher: | Microbiology Society |
Identification Number: | 10.1099/vir.0.000066 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:87704 |