Lashen, H., Jones, G.L., Duru, C. et al. (4 more authors) (2013) Bowel dysfunction after total abdominal hysterectomy for benign conditions: a prospective longitudinal study. European Journal of Gastroenterology and Hepatology, 25 (10). 1217 - 1222. ISSN 0954-691X
Abstract
BACKGROUND AND AIM: On the basis of retrospective studies, hysterectomy has been considered a risk factor for functional bowel disorders. The aim of this study was to prospectively evaluate the patients' bowel function and general health-related quality of life (QoL) before and after hysterectomy. Our hypothesis was that hysterectomy in properly selected patients can impact positively on the patients' self-reporting of their general health and bowel function.
MATERIALS AND METHODS: A prospective longitudinal observational study was conducted in a university-based teaching hospital. Eighty-five patients who were scheduled for total abdominal hysterectomy for a nonmalignant cause completed the study. The main outcome measure was the patient's perception of her bowel function, which was assessed preoperatively and at 6, 12, 26 and 52 weeks postoperatively using the gastrointestinal quality of life questionnaire. The patient's general health was also assessed using a generic general health questionnaire (EQ5D and EQVAS). The effect of time on change in questionnaire score was assessed using mixed model repeated measures at a significance level of 0.05.
RESULTS: The scores in the three questionnaires declined significantly at 6 weeks postoperatively as compared with those obtained preoperatively. However, there was a subsequent increase in the scores up to 12 months postoperatively. Smoking and use of laxative were identified as potential confounding variables.
CONCLUSION: Apart from a transient negative effect, total abdominal hysterectomy improves the patient's gastrointestinal-related QoL, probably as part of general improvement in their QoL.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2013 Lippincott, Williams and Wilkins. This is an author produced version of a paper subsequently published in European Journal of Gastroenterology and Hepatology. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | bowel; dysfunction; function; hysterectomy |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Human Metabolism (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 14 Jul 2015 14:43 |
Last Modified: | 23 Mar 2018 05:55 |
Published Version: | http://dx.doi.org/10.1097/MEG.0b013e328362dc5e |
Status: | Published |
Publisher: | Lippincott, Williams & Wilkins |
Identification Number: | 10.1097/MEG.0b013e328362dc5e |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:86771 |