Sethi, N, MacLennan, K, Wood, HM et al. (1 more author) (2016) The past and future impact of next-generation sequencing in head and neck cancer. Head & Neck, 38 (S1). E2395-E2402. ISSN 1043-3074
Abstract
Progress in sequencing technology is intrinsically linked to progress in understand cancer genomics. This review aims to discuss the development from Sanger sequencing to next generation sequencing (NGS) technology. We highlight the technical considerations for understanding reports using NGS. We discuss the findings of studies in head and neck cancer using NGS as well as the Cancer Genome Atlas. Finally we discuss future routes for research utilising this methodology and the potential impact of this.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015 Wiley Periodicals,Inc. This is the peer reviewed version of the following article: Sethi, N, MacLennan, K, Wood, HM and Rabbitts, P (2016) The past and future impact of next-generation sequencing in head and neck cancer. Head & neck, 38 (S1). E2395-E2402, which has been published in final form at http://dx.doi.org/10.1002/hed.24085. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Next generation sequencing; head and neck cancer; Sanger sequencing; human papilloma virus; genomics |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Medical Education |
Depositing User: | Symplectic Publications |
Date Deposited: | 18 May 2015 10:08 |
Last Modified: | 25 Oct 2016 22:37 |
Published Version: | http://dx.doi.org/10.1002/hed.24085 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/hed.24085 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:86122 |