Jin, Y., Birlea, S.A., Fain, P.R. et al. (19 more authors) (2010) Common variants in FOXP1 are associated with generalized vitiligo. Nature Genetics, 42 (7). 576 - 578. ISSN 1061-4036
Abstract
In a recent genome-wide association study of generalized vitiligo, we identified ten confirmed susceptibility loci. By testing additional loci that showed suggestive association in the genome-wide study, using two replication cohorts of European descent, we observed replicated association of generalized vitiligo with variants at 3p13 encompassing FOXP1 (rs17008723, combined P = 1.04 × 10−8) and with variants at 6q27 encompassing CCR6 (rs6902119, combined P = 3.94 × 10−7).
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Copyright © 2010, Rights Managed by Nature Publishing Group. This is an author produced version of a paper subsequently published in Nature Genetics. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Genome-wide association; Essential transcriptional regulator; T-Cells; Susceptibility loci; Autoimmunity; Genetics; Diseases; IDDM8 |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 07 Oct 2015 13:34 |
Last Modified: | 23 Nov 2016 22:59 |
Published Version: | https://doi.org/10.1038/ng.602 |
Status: | Published |
Publisher: | Nature Publishing Group |
Refereed: | Yes |
Identification Number: | 10.1038/ng.602 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:85889 |