Mears, M., Tarmey, D.S. and Geoghegan, M. (2011) Single Macromolecule Diffusion in Confined Environments. Macromolecular Rapid Communications, 32 (18). 1411 - 1418. ISSN 1022-1336
Abstract
We consider the behaviour of single molecules on surfaces and, more generally, in confined environments. These are loosely split into three sections: single molecules in biology, the physics of single molecules on surfaces and controlled (directed) diffusion. With recent advances in single molecule detection techniques, the importance and mechanisms of single molecule processes such as localised enzyme production and intracellular diffusion across membranes has been highlighted, emphasising the extra information that cannot be obtained with techniques that present average behaviour. Progress has also been made in producing artificial systems that can control the rate and direction of diffusion, and because these are still in their infancy (especially in comparison to complex biological systems), we discuss the new physics revealed by these phenomena.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an author produced version of a paper subsequently published in Macromolecular Rapid Communications. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | biomacromolecules; diffusion; surfaces |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Physics and Astronomy (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 06 Oct 2015 13:53 |
Last Modified: | 22 Oct 2015 16:07 |
Published Version: | https://doi.org/10.1002/marc.201100076 |
Status: | Published |
Publisher: | Wiley-VCH Verlag |
Refereed: | Yes |
Identification Number: | 10.1002/marc.201100076 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:85835 |