Lv, L, Guo, Y, Shen, Y et al. (4 more authors) (2015) Intracellularly degradable, self-assembled amphiphilic block copolycurcumin nanoparticles for efficient in vivo cancer chemotherapy. Advanced Healthcare Materials, 4 (10). pp. 1496-1501. ISSN 2192-2640
Abstract
Intracellularly degradable, self-assembled amphiphilic Biotin-PEG-PCDA nanoparticles that display excellent in vivo anticancer efficacy benefitted from their high tumor accumulation and stimuli-triggered intracellular drug release are developed. They can be loaded with other anticancer drugs (e.g. doxorubicin) to exploit the synergy of combinational dual-drug therapy to further enhance in vivo anticancer efficacy.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015, Wiley. This is the peer reviewed version of the following article: “Lv, L., Guo, Y., Shen, Y., Liu, J., Zhang, W., Zhou, D. and Guo, S. (2015), Intracellularly Degradable, Self-Assembled Amphiphilic Block Copolycurcumin Nanoparticles for Efficient In Vivo Cancer Chemotherapy. Advanced Healthcare Materials”, which has been published in final form at http://dx.doi.org/10.1002/adhm.201500075. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
Keywords: | cancer therapy;curcumin;drug delivery;nanomedicine;polycurcumin;self-assembly |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Inorganic Chemistry (Leeds) |
Funding Information: | Funder Grant number European Research Council 331281 EU - European Union 331281 EU - European Union 331281 |
Depositing User: | Symplectic Publications |
Date Deposited: | 19 Jun 2015 11:42 |
Last Modified: | 23 Jun 2016 01:01 |
Published Version: | http://dx.doi.org/10.1002/adhm.201500075 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/adhm.201500075 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:85193 |