Bunce, D orcid.org/0000-0003-3265-2700, Batterham, PJ, Christensen, H et al. (1 more author) (2014) Causal associations between depression symptoms and cognition in a community-based cohort of older adults. American Journal of Geriatric Psychiatry, 22 (12). pp. 1583-1591. ISSN 1064-7481
Abstract
OBJECTIVE: To evaluate the temporal association between depression symptoms and cognitive function in older adults over a 4-year period. METHODS: Using a longitudinal, cross-lagged, population-based design, we studied depression symptoms and cognitive domains (including processing speed, verbal fluency, face and word recognition, episodic memory, and simple and choice reaction time) in 896 community-dwelling adults aged 70-97 years. RESULTS: Cross-lagged structural equation models suggested that initial depression symptoms affected subsequent processing speed and simple and choice reaction time but that cognition did not predict depression symptoms over time. The associations between depression and cognitive variables were attenuated when the models were adjusted for sensory impairment, physical health, and locus of control. CONCLUSION: The findings suggest that, causally, depression precedes cognitive impairment in this age group and that the association is related to physical health and perceptions of a lack of control.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | (c) 2014, Elsevier. This is an author produced version of a paper published in The American Journal of Geriatric Psychiatry. Uploaded in accordance with the publisher's self-archiving policy |
Keywords: | Depression; cognition; old age; physical health; reaction time |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Psychology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 15 May 2015 13:57 |
Last Modified: | 18 Mar 2019 16:49 |
Published Version: | http://dx.doi.org/10.1016/j.jagp.2014.01.004 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.jagp.2014.01.004 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:84448 |