Harris, AT, Rennie, A, Waqar-Uddin, H et al. (7 more authors) (2010) Raman spectroscopy in head and neck cancer. Head and Neck Oncology, 2. 26. ISSN 1758-3284
Abstract
In recent years there has been much interest in the use of optical diagnostics in cancer detection. Early diagnosis of cancer affords early intervention and greatest chance of cure. Raman spectroscopy is based on the interaction of photons with the target material producing a highly detailed biochemical 'fingerprint' of the sample. It can be appreciated that such a sensitive biochemical detection system could confer diagnostic benefit in a clinical setting. Raman has been used successfully in key health areas such as cardiovascular diseases, and dental care but there is a paucity of literature on Raman spectroscopy in Head and Neck cancer. Following the introduction of health care targets for cancer, and with an ever-aging population the need for rapid cancer detection has never been greater. Raman spectroscopy could confer great patient benefit with early, rapid and accurate diagnosis. This technique is almost labour free without the need for sample preparation. It could reduce the need for whole pathological specimen examination, in theatre it could help to determine margin status, and finally peripheral blood diagnosis may be an achievable target.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | (c) 2010, Harris et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Optical coherence tomography; Multivariate-analysis; Neural-networks; Early-diagnosis; Single cells; Tissue; Malignancy; Spectra; Microspectroscopy; Discrimination |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Dentistry (Leeds) > Oral Biology (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Dentistry (Leeds) > Oral Surgery (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 24 Mar 2015 11:54 |
Last Modified: | 22 Jan 2018 15:29 |
Published Version: | http://dx.doi.org/10.1186/1758-3284-2-26 |
Status: | Published |
Publisher: | BioMed Central |
Identification Number: | 10.1186/1758-3284-2-26 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:83715 |
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