Renshaw, S.A. and Ingham, P.W. (2010) Zebrafish models of the immune response: taking it on the ChIn. BMC Biology, 8. 148. ISSN 1741-7007
Abstract
The zebrafish is proving to be an extremely versatile new experimental model for unraveling the mysteries of innate immunity and has considerable promise as a system for the identification of novel modulators of this crucial biological process. A rate-limiting factor, however, is the mechanical stimulus required to induce the inflammatory response. A new chemically induced inflammation assay ('ChIn' assay) published in BMC Biology obviates this requirement and seems set to accelerate progress in the field.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: |
© 2010 Renshaw and Ingham; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | LARVAE |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection and Immunity (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 31 Oct 2014 14:22 |
Last Modified: | 31 Oct 2014 14:22 |
Published Version: | http://dx.doi.org/10.1186/1741-7007-8-148 |
Status: | Published |
Publisher: | BioMed Central |
Refereed: | Yes |
Identification Number: | 10.1186/1741-7007-8-148 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:81323 |