Owen, CB, Hughes, DJ, Baquero-Perez, B et al. (4 more authors) (2014) Utilising proteomic approaches to understand oncogenic human herpesviruses. Molecular and Clinical Oncology, 2 (6). 891 - 903. ISSN 2049-9450
Abstract
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population. These viruses persist for the life of the host and may each contribute to a number of malignancies, for which there are currently no cures. Large‑scale proteomic-based approaches provide an excellent means of increasing the collective understanding of the proteomes of these complex viruses and elucidating their numerous interactions within the infected host cell. These large‑scale studies are important for the identification of the intricacies of viral infection and the development of novel therapeutics against these two important pathogens.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | (c) 2014 Spandidos Publications. Reproduced in accordance with the publisher's self-archiving policy. |
Keywords: | Proteomics; mass spectrometry; γ‑herpesvirus |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Biological Sciences (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 17 Oct 2014 11:29 |
Last Modified: | 03 May 2015 21:34 |
Published Version: | http://dx.doi.org/10.3892/mco.2014.341 |
Status: | Published |
Publisher: | Spandidos Publications |
Identification Number: | 10.3892/mco.2014.341 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:80003 |