Murray, J, Nowak, D, Pukenas, L et al. (6 more authors) (2014) Solid phase synthesis of functionalised SAM-forming alkanethiol-oligoethyleneglycols. Journal of Materials Chemistry B, 2 (24). 3741 - 3744. ISSN 2050-750X
Abstract
We present an efficient solid phase synthesis methodology that provides easy access to a range of functionalised long-chain alkanethiol-oligoethyleneglycols that form well-defined self-assembled monolayers on gold and are compatible with pre- or post-assembly conjugation of (bio)molecules. We demonstrate the versatility of our synthetic route by synthesising LCAT-OEGs with a range of functional moieties, including peptides, electro-active redox groups, chemical handles for post-assembly conjugation of (bio)molecules, and demonstrate the application of our LCAT-OEG monolayers in immunosensing, where they show good biocompatibility with minimal biofouling.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | (c) 2014, Murray, J, Nowak, D, Pukenas, L, Azhar, R, Guillorit, M, Wälti, C, Critchley, K, Johnson, S and Bon, RS. This is an Open Access article distributed in accordance with the Creative Commons Attribution (CC BY 3.0) licence, which permits others to distribute, remix, adapt, build upon this work, and license their derivative works on different terms, provided the original work is properly cited. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) > Pollard Institute (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 23 Jul 2014 11:47 |
Last Modified: | 24 Jul 2014 00:22 |
Published Version: | http://dx.doi.org/10.1039/C4TB00573B |
Status: | Published |
Publisher: | Royal Society of Chemistry |
Identification Number: | 10.1039/C4TB00573B |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:79638 |