Lee, E.C., Whitehead, A.L., Jacques, R.M. et al. (1 more author) (2014) The statistical interpretation of pilot trials: should significance thresholds be reconsidered? BMC MedIcal Research Methodology, 14 (1). 41 .
Abstract
In an evaluation of a new health technology, a pilot trial may be undertaken prior to a trial that makes a definitive assessment of benefit. The objective of pilot studies is to provide sufficient evidence that a larger definitive trial can be undertaken and, at times, to provide a preliminary assessment of benefit.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2014 Lee et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
Keywords: | Pilot trial, Power, Type I error, Confidence interval, Significance, Bayesian methods |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 17 Apr 2014 09:44 |
Last Modified: | 29 Mar 2018 08:09 |
Published Version: | http://dx.doi.org/10.1186/1471-2288-14-41 |
Status: | Published |
Publisher: | BioMed Central |
Identification Number: | 10.1186/1471-2288-14-41 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:78334 |