Threapleton, D, Greenwood, DC, Cleghorn, C et al. (6 more authors) (2013) Dietary fiber intake and risk of first stroke: A systematic review and meta-analysis. Stroke, 44 (5). pp. 1360-1368. ISSN 0039-2499
Abstract
Background and Purpose—Fiber intake is associated with reduced stroke risk in prospective studies, but no meta-analysis has been published to date. Methods—Multiple electronic databases were searched for healthy participant studies reporting fiber intake and incidence of first hemorrhagic or ischemic stroke, published between January 1990 and May 2012. Results—Eight cohort studies from the United States, northern Europe, Australia, and Japan met inclusion criteria. Total dietary fiber intake was inversely associated with risk of hemorrhagic plus ischemic stroke, with some evidence of heterogeneity between studies (I2; relative risk per 7 g/day, 0.93; 95% confidence interval, 0.88–0.98; I2=59%). Soluble fiber intake, per 4 g/day, was not associated with stroke risk reduction with evidence of low heterogeneity between studies, relative risk 0.94 (95% confidence interval, 0.88–1.01; I2=21%). There were few studies reporting stroke risk in relation to insoluble fiber or fiber from cereals, fruit, or vegetables. Conclusions—Greater dietary fiber intake is significantly associated with lower risk of first stroke. Overall, findings support dietary recommendations to increase intake of total dietary fiber. However, a paucity of data on fiber from different foods precludes conclusions regarding the association between fiber type and stroke. There is a need for future studies to focus on fiber type and to examine risk for ischemic and hemorrhagic strokes separately.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2013, owner. This is an author produced version of a paper published in Stroke. Uploaded in accordance with the publisher's self-archiving policy. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Genetics, Health and Therapeutics (LIGHT) > Division of Epidemiology & Biostatistics (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Health Sciences (Leeds) > Nuffield Centre for International Health and Development (Leeds) |
Funding Information: | Funder Grant number Food Standards Agency SACN 01 004 Food Standards Agency SACN 01 004 |
Depositing User: | Symplectic Publications |
Date Deposited: | 09 Dec 2013 12:14 |
Last Modified: | 21 Apr 2016 10:33 |
Published Version: | http://dx.doi.org/10.1161/STROKEAHA.111.000151 |
Status: | Published |
Publisher: | American Heart Association |
Identification Number: | 10.1161/STROKEAHA.111.000151 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:76496 |