Boylan, SM, Cade, JE, Kirk, SF et al. (6 more authors) (2008) Assessing caffeine exposure in pregnant women. The British Journal of Nutrition: an international journal of nutritional science, 100 (4). 875 - 882 . ISSN 0007-1145
Abstract
Studies on the effects of caffeine on health, while numerous, have produced inconsistent results. One of the most uncertain and controversial effects is on pregnancy outcome. Studies have produced conflicting results due to a number of methodological variations. The major challenge is the accurate assessment of caffeine intake. The aim of the present study was to explore different methods of assessing caffeine exposure in pregnant women. Twenty-four healthy pregnant women from the UK city of Leeds completed both a detailed questionnaire, the caffeine assessment tool (CAT) designed specifically to assess caffeine intake and a prospective 3 d food and drink diary. The women also provided nine saliva samples over two consecutive days for estimation of caffeine and a metabolite (paraxanthine). Caffeine intakes from the CAT and diary showed adequate agreement (intra-class correlation coefficient of 0.5). For saliva caffeine and paraxanthine measures, the between-sample variation (within the same woman) was greater than between-woman and between-day variation. However, there was still adequate agreement between these measures and the CAT. The CAT is a valuable tool that is now being used in a large prospective study investigating caffeine's role in pregnancy outcome.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2008, Nutrition Society. Reproduced in accordance with the publisher's self-archiving policy. |
Keywords: | Adult, biological markers, caffeine, diet records, female, food habits, humans, pregnancy, pregnancy outcome, pregnancy trimesters, prospective studies, questionnaires, saliva, sensitivity and specificity, theophylline |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Epidemiology and Biostatistics (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 06 Jun 2013 13:00 |
Last Modified: | 29 Oct 2016 17:29 |
Published Version: | http://dx.doi.org/10.1017/S0007114508939842 |
Status: | Published |
Publisher: | Nutrition Society |
Identification Number: | 10.1017/S0007114508939842 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:75604 |