Mandal, PK, Branson, TR, Hayes, ED et al. (4 more authors) (2012) Towards a structural basis for the relationship between blood group and the severity of El Tor cholera. Angewandte Chemie International Edition, 51 (21). 5143 - 5146 . ISSN 1433-7851
Abstract
It has long been known that people with blood group O are more severely affected by El Tor cholera than those with blood groups A or B. Microcalorimetry and NMR spectroscopy are used to evaluate the ability of the B-subunits of cholera toxin and E. coli heat-labile toxin to bind to selected blood group oligosaccharides.
Metadata
| Item Type: | Article |
|---|---|
| Authors/Creators: |
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| Keywords: | ABO Blood-Group System, Carbohydrate Sequence, Cholera, Cholera Toxin, Humans, Models, Molecular, Molecular Sequence Data |
| Dates: |
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| Institution: | The University of Leeds |
| Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) |
| Depositing User: | Symplectic Publications |
| Date Deposited: | 15 Feb 2013 09:37 |
| Last Modified: | 04 Nov 2016 03:18 |
| Published Version: | http://dx.doi.org/10.1002/anie.201109068 |
| Status: | Published |
| Publisher: | Wiley Verlag |
| Identification Number: | 10.1002/anie.201109068 |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:74913 |
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