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Hernández Alava, M., Wailoo, A.J. and Ara, R. (2010) Tails from the Peak District: adjusted censored mixture models of EQ-5D health state utility values. Discussion Paper. HEDS Discussion Paper 10/08 .
Abstract
Health state utility data generated using the EQ-5D instrument are typically right bounded at one with a substantial gap to the next set of observations, left bounded by some negative value, and are multi modal. These features present challenges to the estimation of the e¤ect of clinical and socioeconomic characteristics on health utilities. We present an adjusted censored model and then use this in a flexible, mixture modelling framework to address these issues. We demonstrate superior performance of this model compared to linear regression and Tobit censored regression using a dataset from repeated observations of patients with rheumatoid arthritis. We �nd that three latent classes are appropriate in estimating EQ-5D from function, pain and sociodemographic factors. Analysis of utility data should apply methods that recognise the distributional features of the data.
Metadata
Item Type: | Monograph |
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Authors/Creators: |
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Keywords: | Mixture models, latent class model, censored regression, EQ-5D, mapping |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > Health Economics and Decision Science > HEDS Discussion Paper Series |
Depositing User: | ScHARR / HEDS (Sheffield) |
Date Deposited: | 12 Oct 2012 13:58 |
Last Modified: | 09 Jun 2014 07:39 |
Status: | Published |
Series Name: | HEDS Discussion Paper 10/08 |
Identification Number: | HEDS Discussion Paper 10/08 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:74602 |
Available Versions of this Item
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Tails from the Peak District: adjusted censored mixture models of EQ-5D health state utility values. (deposited 04 Aug 2010 08:26)
- Tails from the Peak District: adjusted censored mixture models of EQ-5D health state utility values. (deposited 12 Oct 2012 13:58) [Currently Displayed]