Webb, B S, Tinsley, C J, Barraclough, N E orcid.org/0000-0003-2818-326X et al. (2 more authors) (2003) Gain control from beyond the classical receptive field in primate primary visual cortex. Visual neuroscience. pp. 221-230. ISSN 0952-5238
Abstract
Gain control is a salient feature of information processing throughout the visual system. Heeger (1991, 1992) described a mechanism that could underpin gain control in primary visual cortex (VI). According to this model, a neuron's response is normalized by dividing its output by the sum of a population of neurons, which are selective for orientations covering a broad range. Gain control in this scheme is manifested as a change in the semisaturation constant (contrast gain) of a VI neuron. Here we examine how flanking and annular gratings of the same or orthogonal orientation to that preferred by a neuron presented beyond the receptive field modulate gain in V1 neurons in anesthetized marmosets (Callithrix jacchus). To characterize how gain was modulated by surround stimuli, the Michaelis-Menten equation was fitted to response versus contrast functions obtained under each stimulus condition. The modulation of gain by surround stimuli was modelled best as a divisive reduction in response gain. Response gain varied with the orientation of surround stimuli, but was reduced most when the orientation of a large annular grating beyond the classical receptive field matched the preferred orientation of neurons. The strength of surround suppression did not vary significantly with retinal eccentricity or laminar distribution. In the mannoset, as in macaques (Angelucci et al., 2002a,b), gain control over the sort of distances reported here (up to 10 deg) may be mediated by feedback from extrastriate areas.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | marmoset,primary visual cortex,receptive field,gain,context,MACAQUE V1 NEURONS,CAT STRIATE CORTEX,FUNCTIONAL ARCHITECTURE,INTRINSIC CONNECTIONS,ORIENTATION SELECTIVITY,CONTEXTUAL MODULATION,RESPONSE MODULATION,SPATIAL SUMMATION,CORTICAL-NEURONS,ALERT MONKEYS |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 07 Jun 2012 17:01 |
Last Modified: | 16 Oct 2024 12:13 |
Published Version: | https://doi.org/10.1017/S0952523803203011 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1017/S0952523803203011 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:64403 |