Seavers, P R, Lewis, R J, Brannigan, J A et al. (1 more author) (2001) Crystallization and preliminary X-ray analysis of the sporulation factor SpoIIAA in its native and phosphorylated forms. Acta Crystallographica. Section D, Biological Crystallography. pp. 292-295. ISSN 1399-0047
Abstract
Sporulation in Bacillus begins with an asymmetric cell division producing two progeny with identical chromosomes but different developmental fates. As such, it is a simple example of cellular differentiation. The establishment of cell type is controlled by a series of alternate RNA polymerase sigma subunits. The first compartment-specific sigma factor is sigma (F), whose activity is controlled by SpoIIAB, an anti-sigma factor, and SpoIIAA, an anti-sigma factor antagonist which is phosphorylated by the kinase activity of SpoIIAB. Here, the preliminary crystallographic analysis of SpoIIAA and phosphorylated SpoIIAA from B. sphaericus in forms suitable for high-resolution structure determination are reported.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Copyright © 2001 International Union of Crystallography - http://www.iucr.org/cgi-bin/paper?ad0136 |
Keywords: | TRANSCRIPTION FACTOR SIGMA(F),BACILLUS-SUBTILIS |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Sherpa Assistant |
Date Deposited: | 11 May 2005 |
Last Modified: | 16 Oct 2024 11:58 |
Published Version: | https://doi.org/10.1107/S090744490001859X |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1107/S090744490001859X |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:455 |