Parsons, H. K. and Dockrell, D. H. (2002) The burden of invasive pneumococcal disease and the potential for reduction by immunisation. International journal of antimicrobial agents, 19 (2). pp. 85-93. ISSN 0924-8579
Abstract
Streptococcus pneumoniae causes invasive disease world-wide and in all age groups. The reported incidence varies geographically and is increased in certain population groups. The incidence is highest in children less than 2 years and is also increased in the elderly. Mortality remains substantial even in the developed world despite appropriate antimicrobial therapy. The emergence of penicillin-resistant pneumococci highlights the importance of immunisation as a means to prevent disease. This review discusses the burden of invasive pneumococcal disease, identifies high-risk patients and analyses evidence for vaccine efficacy and cost-effectiveness.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) |
Depositing User: | Miss Anthea Tucker |
Date Deposited: | 29 Mar 2012 09:44 |
Last Modified: | 29 Mar 2012 09:44 |
Published Version: | http://dx.doi.org/10.1016/S0924-8579(01)00491-5 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/S0924-8579(01)00491-5 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:43822 |