Tunbridge, A. J., Stevanin, T. M., Lee, M. et al. (4 more authors) (2006) Inhibition of macrophage apoptosis by Neisseria meningitidis requires nitric oxide detoxification mechanisms. Infection and immunity, 74 (1). pp. 729-733. ISSN 0019-9567
Abstract
Host-driven macrophage apoptosis contributes to innate immunity during bacterial infection. Neisseria meningitidis inhibits apoptosis in a variety of cells, but its impact on macrophage apoptosis is unknown. We demonstrate that N. meningitidis prevents macrophage apoptosis via genes encoding nitric oxide detoxification and a porin, PorB.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) |
Depositing User: | Miss Anthea Tucker |
Date Deposited: | 29 Mar 2012 09:48 |
Last Modified: | 29 Mar 2012 09:48 |
Published Version: | http://dx.doi.org/10.1128/IAI.74.1.729-733.2006 |
Status: | Published |
Publisher: | American Society for Microbiology |
Identification Number: | 10.1128/IAI.74.1.729-733.2006 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:43812 |
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