Kariuki, T.M., Farah, I.O., Yole, D.S. et al. (5 more authors) (2004) Parameters of the attenuated schistosome vaccine evaluated in the olive baboon. Infection and Immunity. pp. 5526-5529. ISSN 1098-5522
Abstract
Five exposures of baboons to the attenuated schistosome vaccine gave greater protection than three exposures, but this attenuation was not sustained when challenge was delayed. Within the scope of the data collected, fecal egg counts and circulating antigen levels did not accurately predict the observed worm burdens. Levels of immunoglobulin G at challenge correlated best with protection, but there was little evidence of a recall response.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Copyright © 2004, American Society for Microbiology |
Keywords: | IRRADIATED CERCARIA VACCINE,CIRCULATING ANODIC ANTIGEN,PAPIO-ANUBIS,MONOCLONAL-ANTIBODIES,PROTECTIVE IMMUNITY,MANSONI,RESPONSES |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Biology (York) |
Depositing User: | Sherpa Assistant |
Date Deposited: | 04 Mar 2005 |
Last Modified: | 16 Oct 2024 11:51 |
Published Version: | https://doi.org/10.1128/IAI.72.9.5526-5529.2004 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1128/IAI.72.9.5526-5529.2004 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:331 |