Modi, N. and Wilcox, M.H. (2001) Evidence for antibiotic induced Clostridium perfringens diarrhoea. Journal of Clinical Pathology, 54 (10). pp. 748-751. ISSN 0021-9746
Abstract
Clostridium difficile is a well documented cause of antibiotic associated diarrhoea in hospitalised patients, but may account for only approximately 20% of all cases. This leader reviews the current knowledge and understanding of the pathogenesis, epidemiology, and diagnosis of non-food borne Clostridium perfringens diarrhoea. Although enterotoxigenic C perfringens has been implicated in some C difficile negative cases of antibiotic associated diarrhoea, C perfringens enterotoxin detection methods are not part of the routine laboratory investigation of such cases. Testing for C perfringens enterotoxin in faecal samples from patients with antibiotic associated diarrhoea and sporadic diarrhoea on a routine basis would have considerable resource implications. Therefore, criteria for initiating investigations and optimum laboratory tests need to be established. In addition, establishing the true burden of C perfringens antibiotic associated diarrhoea is important before optimum control and treatment measures can be defined.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2001 Journal of Clinical Pathology |
Keywords: | Clostridium perfringens, Clostridium difficile, hospital acquired infective diarrhoea |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) |
Depositing User: | Sherpa Assistant |
Date Deposited: | 13 Mar 2006 |
Last Modified: | 25 Oct 2016 14:29 |
Published Version: | http://jcp.bmjjournals.com/cgi/content/full/54/10/... |
Status: | Published |
Refereed: | Yes |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:256 |