Mafirakureva, N. orcid.org/0000-0001-9775-6581, Marenah, K.S., Burton, A. orcid.org/0000-0002-4416-0538 et al. (12 more authors) (2026) Health economic evaluation of hip fracture care pathways in The Gambia. BMJ Global Health, 11 (9). e022219. ISSN: 2059-7908
Abstract
Hip fractures cause substantial morbidity, mortality and healthcare costs among older adults. While advances in surgical and postoperative care have improved outcomes in high-income countries, these interventions are often inaccessible in low-income and middle-income countries due to cost constraints. This study assessed the costs and outcomes of surgical versus non-surgical management of hip fractures to inform resource allocation in a resource-limited setting. Data from a prospective cohort study of patients with acute hip fractures over a 12-month postfracture follow-up period were used. Outcomes included quality-adjusted life years (QALYs), healthcare resource use and costs in 2024 US$. Differences in costs and QALYs were estimated using multivariable regression analysis, while a range of sensitivity analyses assessed the impact of different assumptions. The analysis included 137 patients with a mean age of 70 years (SD: 13.4); 60% (n=82) were female and 81.8% (n=112) had fragility fractures. Fewer than half (47%, n=64) had surgery. Surgical management incurred US$988 higher costs (95% CI US$843 to US$1132) and generated 0.122 additional QALYs (95% CI −0.034 to 0.277) compared with non-surgical care, yielding an incremental cost-effectiveness ratio (ICER) of US$8117 per QALY gained. The probability of surgery being cost-effective exceeded 50% at willingness-to-pay thresholds of US$8200 per QALY gained or higher. The results were sensitive to surgical timing: operating within 3 days of admission more than doubled health gains to 0.247 QALYs (95% CI 0.056 to 0.439) and reduced the ICER to $4974 per QALY gained compared with no surgery. In this resource-limited setting, surgical management of hip fractures is more expensive but delivers clinically meaningful benefit for patients; a gain of 0.12 QALYs per patient translating to an extra 44 days in good health. Health systems in resource-limited settings should prioritise expanding surgical access while optimising early intervention and postoperative care to maximise benefits.
Metadata
| Item Type: | Article |
|---|---|
| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © Author(s) (or their employer(s)) 2026. Re- use permitted under CC BY. https://creativecommons.org/licenses/by/4.0/ |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
| Date Deposited: | 05 Oct 2026 13:43 |
| Last Modified: | 05 Oct 2026 13:43 |
| Status: | Published |
| Publisher: | BMJ |
| Refereed: | Yes |
| Identification Number: | 10.1136/bmjgh-2025-022219 |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:246295 |
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Filename: e022219.full.pdf
Licence: CC-BY 4.0

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