Pan, J., Liu, C., Wu, J. et al. (6 more authors) (2025) MedVLM-R1: Incentivizing Medical Reasoning Capability of Vision-Language Models (VLMs) via reinforcement learning. In: Gee, J.C., Alexander, D.C., Hong, J., Iglesias, J.E., Sudre, C.H., Venkataraman, A., Golland, P., Kim, J.H. and Park, J., (eds.) Medical Image Computing and Computer Assisted Intervention – MICCAI 2025: 28th International Conference, Daejeon, South Korea, September 23–27, 2025, Proceedings, Part VII. 28th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2025), 23-27 Sep 2025, Daejeon, Republic of Korea. Lecture Notes in Computer Science, vol. LNCS 15966. Springer Nature Switzerland, pp. 337-347. ISBN: 9783032049803. ISSN: 0302-9743. EISSN: 1611-3349.
Abstract
Reasoning is a critical frontier for advancing medical image analysis, where transparency and trustworthiness play a central role in both clinician trust and regulatory approval. Although Medical Visual Language Models (VLMs) show promise for radiological tasks, most existing VLMs merely produce final answers without revealing the underlying reasoning. To address this gap, we introduce MedVLM-R1, a medical VLM that explicitly generates natural language reasoning to enhance transparency and trustworthiness. Instead of relying on supervised fine-tuning (SFT), which often suffers from overfitting to training distributions and fails to foster genuine reasoning, MedVLM-R1 employs a reinforcement learning framework that incentivizes the model to discover human-interpretable reasoning paths without using any reasoning references. Despite limited training data (600 visual question answering samples) and model parameters (2B), MedVLM-R1 boosts accuracy from 55.11% to 78.22% across MRI, CT, and X-ray benchmarks, outperforming larger models trained on over a million samples. It also demonstrates robust domain generalization under out-of-distribution tasks. By unifying medical image analysis with explicit reasoning, MedVLM-R1 marks a pivotal step toward trustworthy and interpretable AI in clinical practice.
Metadata
| Item Type: | Proceedings Paper |
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| Copyright, Publisher and Additional Information: | © 2026 The Authors. Except as otherwise noted, this author-accepted version of a conference paper published in Medical Image Computing and Computer Assisted Intervention – MICCAI 2025: 28th International Conference, Daejeon, South Korea, September 23–27, 2025, Proceedings, Part VII is made available via the University of Sheffield Research Publications and Copyright Policy under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Information and Computing Sciences; Artificial Intelligence; Machine Learning; Machine Learning and Artificial Intelligence; Eye Disease and Disorders of Vision; Biomedical Imaging; Medical reasoning; Reinforcement learning; VLMs |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Computer Science (Sheffield) |
| Date Deposited: | 03 Sep 2026 15:18 |
| Last Modified: | 03 Sep 2026 15:18 |
| Status: | Published |
| Publisher: | Springer Nature Switzerland |
| Series Name: | Lecture Notes in Computer Science |
| Refereed: | Yes |
| Identification Number: | 10.1007/978-3-032-04981-0_32 |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:245026 |
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