Mavacamten inhibits myosin activity by stabilizing the myosin interacting-heads motif and stalling motor force generation

Metadata

Item Type:	Article
Authors/Creators:	McMillan, S. Pitts, J. R. T. Barua, B. Winkelmann, D. A. Scarff, C. A. https://orcid.org/0000-0001-6168-0060
Copyright, Publisher and Additional Information:	Copyright © 2026 the Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. no claim to original U.S.Government Works. Distributed under a Creative Commons Attribution license 4.0 (CC-BY).
Dates:	Accepted: 26 March 2026 Published (online): 29 April 2026 Published: 1 May 2026
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Funding Information:	Funder Grant number Royal Society * USE 813030 * RGS\R1\231276 BBSRC C/o RCUK Shared Services UKRI1958 Medical Research Council (MRC) KRISTAL UKRI581
Date Deposited:	06 Aug 2026 09:15
Last Modified:	06 Aug 2026 09:15
Published Version:	https://www.science.org/doi/10.1126/sciadv.aea9335
Status:	Published
Publisher:	American Association for the Advancement of Science
Identification Number:	10.1126/sciadv.aea9335
Related URLs:	Dataset
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:243489

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