Augmented reality rehabilitation at home for adults with Parkinson's disease: a feasibility study

Objective

This study aimed to investigate the use of Strolll, a novel cueing-based rehabilitation programme for PwP, delivered through augmented reality headsets at home.

Methods

Thirty PwP were recruited. Each participant had baseline and follow-up assessments in clinic. Individual game-based rehabilitation was prescribed for home use for 6 weeks with remote monitoring and weekly telephone appointments. The primary outcome measure was the Timed-Up-and-Go (TUG). Secondary outcome measures included the Lindop Parkinson’s Assessment Scale (LPAS). Statistical analysis comprised parametric and non-parametric methods appropriate to the data.

Results

Twenty-eight participants completed 6 weeks’ rehabilitation; two participants withdrew. Mean TUG improved from 13.2s to10.3s (p < 0.001) and LPAS improved from 27 to 29 (p < 0.01). No falls, near falls or other adverse events were reported.

Conclusion

Novel game-based exercises through augmented reality were successfully used to deliver rehabilitation for PwP in their homes with participants’ mobility improved and no adverse effects reported. A multi-site randomised controlled trial (NIHR206530) based on the results of this feasibility trial has started, which will investigate the clinical- and cost-effectiveness of this technology.

Trial Registration: ClinicalTrials.gov No.: NCT05794542 Registered 29-10-2023