Qi, M.-Y. orcid.org/0000-0003-3937-1987, Tan, C.-L. orcid.org/0009-0000-2934-4243, Tang, Z.-R. orcid.org/0000-0002-6564-3539 et al. (3 more authors) (2026) Efficient methanol upcycling to ethylene glycol and glycolaldehyde via divergent C−C coupling synthesis. Nature Communications. ISSN: 2041-1723
Abstract
Direct photocatalytic conversion of methanol into high-value multi-carbon chemicals through precisely controlled C - C coupling represents an extremely appealing but challenging goal. Herein, we demonstrate the efficient photoredox-driven dehydrocoupling of methanol into divergent synthesis of ethylene glycol and glycolaldehyde concomitantly with H2 production by structural regulation of atomically dispersed Ni species. We showcase distinctly different reaction pathway for divergent C - C coupling of methanol over two types of atomically dispersed Ni cocatalyst-decorated SiO quantum dots, namely those with single Ni atoms (Ni1-SiO/SiO2) and Ni clusters (Nin-CdS/SiO2). The Ni1-CdS/SiO2 generates ethylene glycol with 90% selectivity by a radical homo-coupling pathway, whereas the Nin-CdS/SiO2 achieves 96% selectivity towards glycolaldehyde by a radical addition-elimination pathway. This work not only offers a fascinating nonpetroleum route for the divergent C-C coupling synthesis of ethylene glycol and glycolaldehyde but also underscores the broad vista of modulating non-selective radicals toward selective transformation of methanol into multi-carbon products.
Metadata
| Item Type: | Article |
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| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © 2026 The Authors. Except as otherwise noted, this author-accepted version of a journal article published in Nature Communications is made available via the University of Sheffield Research Publications and Copyright Policy under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ © The Author(s) 2026. Open Access: This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. |
| Keywords: | Chemical Sciences; Physical Chemistry |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > School of Mathematical and Physical Sciences |
| Date Deposited: | 17 Mar 2026 20:44 |
| Last Modified: | 17 Mar 2026 20:44 |
| Status: | Published online |
| Publisher: | Springer Science and Business Media LLC |
| Refereed: | Yes |
| Identification Number: | 10.1038/s41467-026-69656-x |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:239211 |
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