Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells

Li, Zhen, Chawla, Himanshi, Di Vagno, Lucia et al. (22 more authors) (2026) Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells. NATURE CHEMICAL BIOLOGY. ISSN: 1552-4450

Metadata

Item Type: Article
Authors/Creators:
  • Li, Zhen
  • Chawla, Himanshi
  • Di Vagno, Lucia
  • Ni Cheallaigh, Aisling
  • Critcher, Meg
  • Sammon, Douglas
  • Gonzalez-Rodriguez, Edgar
  • Briggs, David
  • Chung, Nara
  • Chang, Vincent
  • Mahoney, Keira
  • Cioce, Anna
  • Bineva-Todd, Ganka
  • Wang, Pei-Ying
  • Liu, Yi-Chang
  • Murphy, Lloyd Declan
  • Chen, Yen-Shi
  • Narimatsu, Yoshiki
  • Miller, Rebecca
  • WILLEMS, LIANNE IRENE ORCID logo https://orcid.org/0000-0001-5411-1329
  • Malaker, Stacy
  • Huang, Mia
  • Miller, Gavin J.
  • Hohenester, Erhard
  • Schumann, Benjamin
Copyright, Publisher and Additional Information:

© The Author(s) 2026

Dates:
  • Accepted: 21 November 2025
  • Published (online): 20 January 2026
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Chemistry (York)
Funding Information:
Funder
Grant number
EUROPEAN COMMISSION
851448
Date Deposited: 04 Feb 2026 12:00
Last Modified: 04 Feb 2026 12:00
Published Version: https://doi.org/10.1038/s41589-025-02113-w
Status: Published online
Refereed: Yes
Identification Number: 10.1038/s41589-025-02113-w
Open Archives Initiative ID (OAI ID):

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Filename: s41589-025-02113-w.pdf

Description: Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells

Licence: CC-BY 2.5

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