Griffiths, M. orcid.org/0009-0000-0172-0024, Austin, C. orcid.org/0000-0002-1921-5947, Dekker, J. orcid.org/0000-0001-5631-0698 et al. (2 more authors) (2026) Seeing into Hi-C: How our scientific connectivity revealed the close connections in our DNA to be a work of art. Biophysics Reviews, 7 (1). 012101. ISSN: 2688-4089
Abstract
Scientific data can be beautiful. An example where the data itself have a particularly striking appearance even before any scientific meaning has been ascribed is the so-called “Hi-C” chromatin interaction map with its distinct checker-board patterns which when combined with simulations have revealed the complex structure of the folded genome. Here, we describe an art-science collaboration which arose through combining local and global inter-personal connections, and which illustrates the equivalent short- and long-range contacts within folded genomes.
Metadata
| Item Type: | Article |
|---|---|
| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © 2026 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Molecular motor; Graphene; Geometric topology; Living systems; Chromatin; Cell cycle; Human genome; Chromosomes |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > School of Mathematical and Physical Sciences |
| Date Deposited: | 05 Feb 2026 11:51 |
| Last Modified: | 05 Feb 2026 11:51 |
| Status: | Published |
| Publisher: | AIP Publishing |
| Refereed: | Yes |
| Identification Number: | 10.1063/5.0283280 |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:237475 |
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Filename: 012101_1_5.0283280.pdf
Licence: CC-BY 4.0

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