Schmidt, M.Y., Cuervo, A.M., Double, K.L. et al. (12 more authors) (2026) Unraveling the intersection of aging and Parkinson’s disease: a collaborative roadmap for advancing research models. npj Parkinson's Disease, 12. 28. ISSN: 2373-8057
Abstract
Aging is the most significant risk factor for Parkinson’s disease (PD), yet its role remains underexplored. The International Network for Parkinson’s Disease Modelling and Aging (PD-AGE), funded by the Michael J. Fox Foundation, was established to address these challenges. Through collaborative efforts, the PD-AGE mouse-model working group developed a roadmap to prioritize mouse models, reach consensus on experimental approaches, and standardize protocols to investigate the intersection of aging and PD.
Metadata
| Item Type: | Article |
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| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © The Author(s) 2026. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| Keywords: | Neuroscience; Parkinson's disease; Risk factors |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
| Funding Information: | Funder Grant number MICHAEL J FOX FOUNDATION MJFF-022769 |
| Date Deposited: | 29 Jan 2026 15:49 |
| Last Modified: | 29 Jan 2026 15:49 |
| Status: | Published |
| Publisher: | Springer Science and Business Media LLC |
| Refereed: | Yes |
| Identification Number: | 10.1038/s41531-025-01239-x |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:237146 |
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