Invited commentary on the importance of endothelial TRPV4 ion channel in myocardial ischemia-reperfusion

Transient receptor potential vallinoid subfamily 4 (TRPV₄) channels are increasingly recognised as critical regulators in cardiovascular diseases. A recent article published by Zhang et al. in CJC identifies TRPV₄ as a key determinant of endothelial integrity during Ischemia-reperfusion, consolidating its potential as a therapeutic target.