IgG4-related periaortitis presenting as left flank pain

Abstract

We present the case of periaortitis which presented initially with left flank pain. A diagnosis of IgG4-related disease (IgG4-RD) was subsequently made and managed as such. IgG4-RD is rare, can be difficult to diagnose, and requires clinical, serological, radiological and pathological correlation, particularly given that serum IgG4 levels may be normal. Immunosuppression is the mainstay treatment for this chronic condition alongside regular rheumatology input.

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Item Type:	Article
Authors/Creators:	Sharrack, S. Paddock, M. https://orcid.org/0000-0003-4508-8803
Copyright, Publisher and Additional Information:	© 2023 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords:	Autoimmunity; IgG4-related disease; Immunoglobulins; Retroperitoneal fibrosis; Sialadenitis
Dates:	Accepted: 2 November 2023 Published (online): 22 November 2023 Published: February 2024
Institution:	The University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Date Deposited:	13 Nov 2025 10:25
Last Modified:	13 Nov 2025 10:25
Published Version:	https://doi.org/10.1016/j.radcr.2023.11.003
Status:	Published
Publisher:	Elsevier BV
Refereed:	Yes
Identification Number:	10.1016/j.radcr.2023.11.003
Related URLs:	PubMed URL
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:234445

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IgG4-related periaortitis presenting as left flank pain

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