Carbapenemase-producing Enterobactericeae screening: Focused patient insights

Background: Anti-microbial resistance (AMR) is predicted to cause 10 million deaths annually by 2050. This prediction has shaped local policies, with a focus on antimicrobial stewardship and source isolation. However, the impact of these interventions on the individual patient is often overlooked, and the patient perspective is infrequently included in AMR strategies. Aim(s)/Objective(s): Our objective was to explore the lived patient experience through a Carbapemase Producing Enterobacterales (CPE) Outbreak. Specifically, we aimed to understand the patient's knowledge of CPE, risks associated with AMR and their experience with rectal screening and source isolation. Method(s): Using a PPIE (public and patient involvement and engagement) framework, during a CPE outbreak, we engaged in one to one conversations with adult inpatients who had capacity, discussing the effects of AMR exposure. CPE-positive (n = 8) and CPE-negative (n = 2) participants were included. The latter had undergone > 3 CPE screens, were high-risk of AMR acquisition and in source isolation. Results: Our one-on-one conversations revealed poor levels of patient knowledge about CPE and AMR risk, with many participants expressing concerns about the limited or lack of information provided by healthcare providers. Experiences with rectal screening was generally reported as uncomfortable, with passive acceptance for it. Opinions on source isolation were mixed, with feelings of being bored or lonely emerging as a common sentiment. Discussion and/or Conclusion(s): These discussions underscore the necessity for improved patient education and communication surrounding CPE and antibiotic resistance, specifically tailored to meet the needs of frailer populations. This study also highlights the critical role of healthcare staff in consistently providing clear information to patients. It is vital patient empowerment is encouraged, and focused efforts made to close this knowledge gap and enhance the patient experience.