metaSHARK: a WWW platform for interactive exploration of metabolic networks

Abstract

The metaSHARK (metabolic search and reconstruction kit) web server offers users an intuitive, fully interactive way to explore the KEGG metabolic network via a WWW browser. Metabolic reconstruction information for specific organisms, produced by our automated SHARKhunt tool or from other programs or genome annotations, may be uploaded to the website and overlaid on the generic network. Additional data from gene expression experiments can also be incorporated, allowing the visualization of differential gene expression in the context of the predicted metabolic network. metaSHARK is available at http://bioinformatics.leeds.ac.uk/shark/.

Metadata

Item Type:	Article
Authors/Creators:	Hyland, C. Pinney, J.W. McConkey, G.A. https://orcid.org/0000-0001-6529-794X Westhead, D.R. https://orcid.org/0000-0002-0519-3820
Keywords:	Animals; Gene Expression Profiling; Metabolism; Models, Biological; Computer Graphics; Internet; Software; User-Computer Interface
Dates:	Accepted: 21 March 2006 Published (online): 1 July 2006 Published: 1 July 2006
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biology (Leeds) The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Date Deposited:	09 Mar 2026 16:32
Last Modified:	09 Mar 2026 16:32
Status:	Published
Publisher:	Oxford University Press
Identification Number:	10.1093/nar/gkl196
Related URLs:	Author
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:233397

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metaSHARK: a WWW platform for interactive exploration of metabolic networks

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