Wang, Y., Lv, X., Laestadius, L.I. et al. (10 more authors) (2025) E-Cigarette Sales to School-Uniformed Adolescents in China: A Randomized Clinical Trial. JAMA Network Open, 8 (10). e2535623. ISSN: 2574-3805
Abstract
Importance: Electronic cigarettes (e-cigarettes) are appealing to adolescents, but sale of e-cigarettes to individuals younger than 18 years is prohibited in China. The effect of school uniforms on e-cigarette sales to adolescents has not been explored.
Objective: To study e-cigarette sales to adolescents wearing school uniforms compared with those wearing casual attire.
Design, Setting, and Participants: This 2-arm randomized clinical trial involved adolescent mystery shoppers wearing school uniforms or casual attire who attempted to purchase e-cigarettes. The trial was conducted across 36 major metropolitan areas in China from July 29 to September 3, 2023. Adolescent buyers aged 18 to 19 years were randomly assigned to wear 1 of the 2 attire types. A 1:1 matching of e-cigarette and cigarette stores was also performed.
Intervention: Adolescent buyers attempting to purchase e-cigarettes while wearing school uniforms were the intervention group, and those in casual attire served as the control group.
Main Outcomes and Measures: The primary outcome was successful purchase of e-cigarettes. Secondary outcomes assessed whether sellers verbally inquired about the buyer’s age, requested an identification (ID) card for age verification, or dissuaded the buyers from using e-cigarettes. Multivariable logistic regression models identified factors associated with outcomes by attire type, adjusted for buyer, seller, and store characteristics.
Results: The final analytical sample included 1089 visits to e-cigarette stores (543 by adolescents in school uniforms and 546 by those in casual attire) and 1059 visits to cigarette stores. Of the e-cigarette stores visited, 85.4% (95% CI, 80.3%-89.4%) posted external advertising, 39.4% (95% CI, 35.9%-43.0%) were located in shopping malls, 90.8% (95% CI, 87.7%-93.2%) displayed age-of-sale signs, and only 15.0% (95% CI, 9.7%-22.5%) exhibited health warnings specifically for e-cigarettes. The overall success rate of adolescents purchasing e-cigarettes without age verification was 78.3% (95% CI, 75.8%-80.6%), significantly lower than the 94.5% (95% CI, 91.3%-96.6%) success rate for purchasing cigarettes without age verification. Adolescents wearing school uniforms had significantly lower odds of successfully purchasing e-cigarettes (adjusted odds ratio [AOR], 0.39; 95% CI, 0.23-0.66) than those in casual attire and were more likely to be asked about their age (AOR, 9.18; 95% CI, 6.46-13.06), requested to show an ID card (AOR, 6.68; 95% CI, 4.53-9.87), and dissuaded from using e-cigarettes (AOR, 1.79; 95% CI, 1.30-2.47). Additionally, when sellers requested ID cards, the probability of successful e-cigarette purchases was significantly lower than when they did not (AOR, 0.02; 95% CI, 0.01-0.03).
Conclusions and Relevance: In this randomized clinical trial of e-cigarette sales, e-cigarettes remained widely sold to adolescents without age verification in China, but wearing a school uniform appeared to reduce adolescents’ ability to purchase e-cigarettes.
Trial Registration: ClinicalTrials.gov Identifier: NCT05962411
Metadata
| Item Type: | Article | 
|---|---|
| Authors/Creators: | 
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| Copyright, Publisher and Additional Information: | © 2025 Wang Y et al. JAMA Network Open. This is an open access article distributed under the terms of the CC-BY License. | 
| Dates: | 
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| Institution: | The University of Leeds | 
| Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) | 
| Date Deposited: | 21 Oct 2025 11:59 | 
| Last Modified: | 21 Oct 2025 11:59 | 
| Status: | Published | 
| Publisher: | American Medical Association (AMA) | 
| Identification Number: | 10.1001/jamanetworkopen.2025.35623 | 
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:233274 | 
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