Current strategies and future directions to enhance recovery following critical illness

Abstract

Improvements in critical care treatments have led to an increased number of survivors of critical illness and an enhanced recognition of the problems which these patients encounter. Despite this, the ideal strategies to both prevent and manage the problems which people face are yet to be fully elucidated.

This review explores the current methods employed to help mitigate problems encountered by survivors of critical illnesses and current barriers that limit their implementation. We will explore the effect of these issues on under-represented communities and the feasibility of delivering these strategies globally, as well as recent advances in mechanistic research and methodological innovation as promising areas for further work. In doing so, it summarises the potential avenues for future research with a view to advancing clinical care and outcomes in survivors of critical illness.

Metadata

Item Type:	Article
Authors/Creators:	Andonovic, M. https://orcid.org/0000-0002-5290-4680 Shaw, M. Hartley, P. Jain, S. Boehm, L. Toth, K. Bourne, R. https://orcid.org/0000-0003-0893-525X Haines, K.J. https://orcid.org/0000-0002-2882-1594 Danesh, V. https://orcid.org/0000-0002-2078-2578 MacTavish, P. Valley, T. Rosa, R.G. Docherty, C. Garrity, K. McCall, P. Tracy, A. Lone, N.I. https://orcid.org/0000-0003-2707-2779 McPeake, J. https://orcid.org/0000-0001-8206-6801
Copyright, Publisher and Additional Information:	© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.
Keywords:	Critical Care
Dates:	Submitted: 31 December 2024 Accepted: 13 August 2025 Published (online): 5 October 2025 Published: 5 October 2025
Institution:	The University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Health Sciences School (Sheffield)
Date Deposited:	17 Oct 2025 10:28
Last Modified:	17 Oct 2025 10:28
Status:	Published online
Publisher:	BMJ
Refereed:	Yes
Identification Number:	10.1136/thorax-2024-221997
Related URLs:	PubMed URL
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:233059

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Current strategies and future directions to enhance recovery following critical illness

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