DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs

van der Sluijs, R.V., Verkennis, A.E.E., Hodskinson, M.R. et al. (17 more authors) (2025) DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs. Nucleic Acids Research, 53 (18). gkaf875. ISSN: 0305-1048

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Item Type: Article
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© The Author(s) 2025. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

Keywords: DNA-Directed DNA Polymerase; DNA Repair; Humans; Nucleotidyltransferases; DNA Damage; Aldehydes; Acrolein; Fanconi Anemia; Proliferating Cell Nuclear Antigen; Cisplatin; Translesion DNA Synthesis
Dates:
  • Accepted: 30 July 2025
  • Published (online): 23 September 2025
  • Published: 23 September 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Mathematical and Physical Sciences
The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield)
Date Deposited: 06 Oct 2025 11:40
Last Modified: 06 Oct 2025 11:40
Status: Published
Publisher: Oxford University Press (OUP)
Refereed: Yes
Identification Number: 10.1093/nar/gkaf875
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