Treatment-related changes in total hip bone mineral density are applicable to trials of varied study designs and to drugs with differing mechanisms of action: meta-regression results from the FNIH-ASBMR SABRE study

Vilaca, T. orcid.org/0000-0002-9227-6076, Lui, L.-Y., Schini, M. orcid.org/0000-0003-2204-2095 et al. (7 more authors) (2025) Treatment-related changes in total hip bone mineral density are applicable to trials of varied study designs and to drugs with differing mechanisms of action: meta-regression results from the FNIH-ASBMR SABRE study. Journal of Bone and Mineral Research. ISSN: 0884-0431

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Item Type: Article
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© 2025 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: surrogate; bone mineral density; fracture; osteoporosis treatment; mechanism of action; sequential therapy; meta-regression; randomised control trial; SABRE
Dates:
  • Accepted: 8 July 2025
  • Published (online): 26 July 2025
  • Published: 26 July 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Date Deposited: 02 Oct 2025 10:13
Last Modified: 02 Oct 2025 10:13
Published Version: https://doi.org/10.1093/jbmr/zjaf100
Status: Published online
Publisher: Oxford University Press (OUP)
Refereed: Yes
Identification Number: 10.1093/jbmr/zjaf100
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