Predicting the heterogeneous chemo-mechano-biological degeneration of cartilage using 3-D biphasic finite elements

Rahman, M.M. orcid.org/0000-0001-9370-3845, Watton, P.N. orcid.org/0000-0002-5531-5953, Neu, C.P. orcid.org/0000-0002-8256-5683 et al. (1 more author) (2025) Predicting the heterogeneous chemo-mechano-biological degeneration of cartilage using 3-D biphasic finite elements. Computer Methods and Programs in Biomedicine, 270. 108902. ISSN: 0169-2607

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Item Type: Article
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© 2025 The Authors. Except as otherwise noted, this author-accepted version of a journal article published in Computer Methods and Programs in Biomedicine is made available via the University of Sheffield Research Publications and Copyright Policy under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/

Keywords: Cartilage; Growth and remodeling; Mathematical modeling; Mechanobiology; Metabolism; Osteoarthritis; Finite Element Analysis; Humans; Cartilage, Articular; Biomechanical Phenomena; Osteoarthritis; Stress, Mechanical; Extracellular Matrix; Computer Simulation; Models, Biological; Chondrocytes
Dates:
  • Accepted: 6 June 2025
  • Published (online): 25 June 2025
  • Published: October 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Computer Science (Sheffield)
Date Deposited: 26 Sep 2025 14:28
Last Modified: 29 Sep 2025 11:26
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.cmpb.2025.108902
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