Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy

Kottke, Timothy, Tonne, Jason, Evgin, Laura et al. (19 more authors) (2021) Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy. Nature Communications. 1930. ISSN: 2041-1723

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Kottke, Timothy
  • Tonne, Jason
  • Evgin, Laura
  • Driscoll, Christopher B
  • van Vloten, Jacob
  • Jennings, Victoria A ORCID logo https://orcid.org/0000-0003-1321-0333
  • Huff, Amanda L
  • Zell, Brady
  • Thompson, Jill M
  • Wongthida, Phonphimon
  • Pulido, Jose
  • Schuelke, Matthew R
  • Samson, Adel
  • Selby, Peter
  • Ilett, Elizabeth
  • McNiven, Mark
  • Roberts, Lewis R
  • Borad, Mitesh J
  • Pandha, Hardev
  • Harrington, Kevin
  • Melcher, Alan
  • Vile, Richard G
Copyright, Publisher and Additional Information:

© The Author(s) 2021

Keywords: Animals,Cancer Vaccines/administration & dosage,Cell Line, Tumor,DNA-Binding Proteins/genetics,Female,Humans,Immunotherapy/methods,Interferon-beta/immunology,Mice, Inbred C57BL,Mutation,Oncolytic Virotherapy/methods,Oncolytic Viruses/immunology,RNA-Binding Proteins/genetics,T-Lymphocytes/immunology,Vesicular stomatitis Indiana virus/immunology,Virus Replication/immunology,Mice
Dates:
  • Accepted: 25 February 2021
  • Published: 26 March 2021
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
The University of York > Faculty of Sciences (York) > Biology (York) > Jack Birch Unit for Molecular Carcinogenesis (York)
Depositing User: Pure (York)
Date Deposited: 28 Aug 2025 15:50
Last Modified: 28 Aug 2025 23:09
Published Version: https://doi.org/10.1038/s41467-021-22115-1
Status: Published
Refereed: Yes
Identification Number: 10.1038/s41467-021-22115-1
Open Archives Initiative ID (OAI ID):

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Filename: s41467-021-22115-1.pdf

Description: s41467-021-22115-1

Licence: CC-BY 2.5

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