McNamara, S. orcid.org/0000-0003-1082-118X, Schneider, P.P. orcid.org/0000-0003-3552-1087, Love-Koh, J. et al. (2 more authors) (2023) Quality-adjusted life expectancy norms for the English population. Value in Health, 26 (2). pp. 163-169. ISSN: 1098-3015
Abstract
Objectives: The National Institute for Health and Care Excellence in England has implemented severity-of-disease modifiers that give greater weight to health benefits accruing to patients who experience a larger shortfall in quality-adjusted life-years (QALYs) under current standard of care than healthy individuals. This requires an estimate of quality-adjusted life expectancy (QALE) of the general population based on age and sex. Previous QALE population norms are based on nearly 30-year-old assessments of health-related quality of life in the general population. This study provides updated QALE estimates for the English population based on age and sex. Methods: 5-level version of EQ-5D data for 14 412 participants from the Health Survey for England (waves 2017 and 2018) were pooled, and health-related quality of life population norms were calculated. These norms were combined with official life tables from the Office for National Statistics for 2017 to 2019 using the Sullivan method to derive QALE estimates based on age and sex. Values were discounted using 0%, 1.5%, and 3.5% discount rates. Results: QALE at birth is 68.24 QALYs for men and 68.21 QALYs for women. These values are significantly lower than previously published QALE population norms based on the older 3-level version of EQ-5D data. Conclusion: This study provides new QALE population norms for England that serve to establish absolute and relative QALY shortfalls for the purpose of health technology assessments.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | EQ-5D; National Institute for Health and Care Excellence; absolute shortfall; population health; proportional shortfall; quality-adjusted life expectancy; quality-adjusted life-year shortfall; Male; Infant, Newborn; Humans; Female; Adult; Quality of Life; Life Expectancy; Quality-Adjusted Life Years; Health Status; Health Surveys |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Funding Information: | Funder Grant number Wellcome Trust Ltd 108903/B/15/Z |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 29 Aug 2025 10:47 |
Last Modified: | 29 Aug 2025 10:47 |
Published Version: | https://doi.org/10.1016/j.jval.2022.07.005 |
Status: | Published |
Publisher: | Elsevier BV |
Refereed: | Yes |
Identification Number: | 10.1016/j.jval.2022.07.005 |
Related URLs: | |
Sustainable Development Goals: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:230752 |