Grogan, Gideon James orcid.org/0000-0003-1383-7056, Li, Jason, Cornish, Katy et al. (2 more authors) (2025) Scalable Biocatalytic Oxygenation of Aliphatic Amine Derivatives Using a Class I Unspecific Peroxygenase. Chemical communications. ISSN: 1364-548X
Abstract
artUPO is revealed as an effective biocatalyst for the regioselective oxygenation of cycloalkylamines to form cyclic amino ketones on preparative scale. Furthermore, amino alcohols can be formed via the selective C-H oxygenation of isopropyl-tethered amine derivatives. Enantiomerically enriched amino alcohols are also accessible using a kinetic resolution approach.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 11 Aug 2025 11:00 |
Last Modified: | 11 Aug 2025 11:00 |
Published Version: | https://doi.org/10.1039/D5CC03882K |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1039/D5CC03882K |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:230290 |